CYP2D6 Testing
Bring Precision to Everyday Prescribing
Integrate CYP2D6 into routine prescribing to improve safety and long-term patient outcomes
Why Adopt CYP2D6 Testing in Clinical Practice ?
CYP2D6 is one of the most clinically significant pharmacogenes, influencing the metabolism of nearly 25% of all prescribed drugs, including oncology, psychiatry, cardiology, and pain management therapies. Incorporating CYP2D6 testing into routine practice allows clinicians to optimize therapy from the outset, preventing treatment failure or severe adverse events.
CYP2D6 CNV Testing:
Key Features & Clinical Relevance
Drug Efficacy & Safety
For prodrugs (e.g. codeine, tamoxifen), too few functional CYP2D6 copies = inadequate activation → reduced efficacy.
For other drugs, excessive copies or ultra-rapid metabolizer phenotypes can lead to too much active drug/metabolite → toxicity.
Clinical Utility & Why It Matters
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